Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow

doi:10.1007/s10483-012-1541-6

Applied Mathematics and Mechanics (English Edition) ›› 2012, Vol. 33 ›› Issue (2): 165-176.doi: https://doi.org/10.1007/s10483-012-1541-6

Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow

Z. MORTAZAVINIA¹, A.ZARE², A. MEHDIZADEH¹

1. Center for Research in Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran;
2. Young Researchers Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran

收稿日期:2011-07-20 修回日期:2011-10-11 出版日期:2012-01-11 发布日期:2012-02-01

Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow

Z. MORTAZAVINIA¹, A.ZARE², A. MEHDIZADEH¹

1. Center for Research in Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran;
2. Young Researchers Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran

Received:2011-07-20 Revised:2011-10-11 Online:2012-01-11 Published:2012-02-01

摘要/Abstract

摘要： The effects of the renal artery stenosis (RAS) on the blood flow and vessel walls are investigated. The pulsatile blood flow through an anatomically realistic model of the abdominal aorta and renal arteries reconstructed from CT-scan images is simulated, which incorporates the fluid-structure interaction (FSI). In addition to the investigation of the RAS effects on the wall shear stress and the displacement of the vessel wall, it is determined that the RAS leads to decrease in the renal mass flow. This may cause the activation of the renin-angiotension system and results in severe hypertension.

Abstract: The effects of the renal artery stenosis (RAS) on the blood flow and vessel walls are investigated. The pulsatile blood flow through an anatomically realistic model of the abdominal aorta and renal arteries reconstructed from CT-scan images is simulated, which incorporates the fluid-structure interaction (FSI). In addition to the investigation of the RAS effects on the wall shear stress and the displacement of the vessel wall, it is determined that the RAS leads to decrease in the renal mass flow. This may cause the activation of the renin-angiotension system and results in severe hypertension.

中图分类号:

76A10

Z. MORTAZAVINIA A.ZARE A. MEHDIZADEH. Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow[J]. Applied Mathematics and Mechanics (English Edition), 2012, 33(2): 165-176.

Z. MORTAZAVINIA;A.ZARE;A. MEHDIZADEH. Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow[J]. Applied Mathematics and Mechanics (English Edition), 2012, 33(2): 165-176.

Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow

Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow

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