The quasi-Green’s function method is used to solve the free vibration problem of clamped thin plates on the Winkler foundation. Quasi-Green’s function is established by the fundamental solution and the boundary equation of the problem. The function satisfies the homogeneous boundary condition of the problem. The mode-shape differential equation of the free vibration problem of clamped thin plates on the Winkler foundation is reduced to the Fredholm integral equation of the second kind by Green’s formula. The irregularity of the kernel of the integral equation is overcome by choosing a suitable form of the normalized boundary equation. The numerical results show the high accuracy of the proposed method.