A class of preconditioned iterative methods, i.e., preconditioned generalized accelerated overrelaxation (GAOR) methods, is proposed to solve linear systems based on a class of weighted linear least squares problems. The convergence and comparison results are obtained. The comparison results show that the convergence rate of the preconditioned iterative methods is better than that of the original methods. Furthermore, the effectiveness of the proposed methods is shown in the numerical experiment.