As it is known, track transportation can be divided into track system above and track system below. While the train is moving, the parts above and below are interacted and influenced. Therefore, in fact, the problem of track transportation is the match between the vehicle and the railway line system. In this paper, on a basis of dynamic analysis of the vehicle-subgrade model of vertical coupled system under primary suspension, utilizing track maintenance standard and simulating track irregularity excitation, the dynamic interaction of vehicle-track-subgrade system is researched in theory and dynamic model of the vertical vehicle-track-subgrade coupled system under secondary suspension is established by compatibility condition of deformation. Even this model considers the actual structure of a vehicle, also considers vibration characteristic of the substructure of track including subgrade and foundation. All these work want to be benefit for understanding and design about the dynamic characters of subgrade in high speed railway.