The problem of checking robust D-stability of multi-in and multi-out (MIMO) systems was studied. Three system models were introduced, i.e. multilinear polynomial matrix, polytopic polynomial matrix and feedback system model. Furthermore, the convex property of each model with respect to the parametric uncertainties was estabilished respectively. Based on this, sufficient conditions for D-stability were expressed in terms of linear matrix inequalities (LMIs) involving only the convex vertices. Therefore, the robust D-stability was tested by solving an LMI optimal problem.