For aerodynamic shape optimization, the approximation management framework (AMF) method is used to organize and manage the variable-fidelity models. The method can take full advantage of the low-fidelity, cheaper models to concentrate the main workload on the low-fidelity models in optimization iterative procedure. Furthermore, it can take high-fidelity, more expensive models to monitor the procedure to make the method globally convergent to a solution of high-fidelity problem. Finally, zero order variable-fidelity aerodynamic optimization management framework and search algorithm are demonstrated on an airfoil optimization of UAV with a flying wing. Compared to the original shape, the aerodynamic performance of the optimal shape is improved. The results show the method has good feasibility and applicability.