Effects of size and location of distal tear on hemodynamics and wave propagation in type B aortic dissection

doi:10.1007/s10483-022-2898-6

Applied Mathematics and Mechanics (English Edition) ›› 2022, Vol. 43 ›› Issue (9): 1449-1468.doi: https://doi.org/10.1007/s10483-022-2898-6

• 论文 • 上一篇

Effects of size and location of distal tear on hemodynamics and wave propagation in type B aortic dissection

Huimin CHEN¹, Qingzhuo CHI¹, Ying HE¹, Lizhong MU¹, Yong LUAN²

1. Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education, School of Energy and Power Engineering, Dalian University of Technology, Dalian 116024, Liaoning Province, China;
2. Department of Anesthesiology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China

收稿日期:2021-12-31 修回日期:2022-07-05 发布日期:2022-08-31
通讯作者: Ying HE, E-mail: heying@dlut.edu.cn
基金资助:
the National Natural Science Foundation of China (No. 51976026) and the Fundamental Research Funds of Central Universities of China (Nos. DUT22YG206 and DUT21JC25)

Effects of size and location of distal tear on hemodynamics and wave propagation in type B aortic dissection

Huimin CHEN¹, Qingzhuo CHI¹, Ying HE¹, Lizhong MU¹, Yong LUAN²

1. Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education, School of Energy and Power Engineering, Dalian University of Technology, Dalian 116024, Liaoning Province, China;
2. Department of Anesthesiology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China

Received:2021-12-31 Revised:2022-07-05 Published:2022-08-31
Contact: Ying HE, E-mail: heying@dlut.edu.cn
Supported by:
the National Natural Science Foundation of China (No. 51976026) and the Fundamental Research Funds of Central Universities of China (Nos. DUT22YG206 and DUT21JC25)

摘要/Abstract

摘要： The type B aortic dissection (TBAD) is a perilous disease with high morbidity and mortality rates. The hemodynamics of TBAD in different scenarios has been widely studied by computational fluid dynamics (CFD) research. However, the flow pattern and wave propagation characteristics in the cardiovascular system with TBAD are not yet clear, and the effect of the distal tear is still unknown. In this work, a one-dimensional (1D) cardiovascular system model coupling with a zero-dimensional (0D) lumped-parameter model is introduced to study the hemodynamics and wave propagation in the cardiovascular system. The results show that the proposed 0D-1D method well captures the oscillation and retrograde characteristics for the flow in the false lumen (FL), and the smaller distal tear damps the retrograde flow. Besides, the distal tear should also be paid attention to, and the wave intensity (WI) can be used as an access mark of the degree of the aortic dissection (AD).

关键词: type B aorta dissection (TBAD), zero-dimensional (0D)-one-dimensional (1D) coupling model, distal tear, flow pattern, wave intensity analysis (WIA)

Abstract: The type B aortic dissection (TBAD) is a perilous disease with high morbidity and mortality rates. The hemodynamics of TBAD in different scenarios has been widely studied by computational fluid dynamics (CFD) research. However, the flow pattern and wave propagation characteristics in the cardiovascular system with TBAD are not yet clear, and the effect of the distal tear is still unknown. In this work, a one-dimensional (1D) cardiovascular system model coupling with a zero-dimensional (0D) lumped-parameter model is introduced to study the hemodynamics and wave propagation in the cardiovascular system. The results show that the proposed 0D-1D method well captures the oscillation and retrograde characteristics for the flow in the false lumen (FL), and the smaller distal tear damps the retrograde flow. Besides, the distal tear should also be paid attention to, and the wave intensity (WI) can be used as an access mark of the degree of the aortic dissection (AD).

Key words: type B aorta dissection (TBAD), zero-dimensional (0D)-one-dimensional (1D) coupling model, distal tear, flow pattern, wave intensity analysis (WIA)

中图分类号:

76D05

Huimin CHEN, Qingzhuo CHI, Ying HE, Lizhong MU, Yong LUAN. Effects of size and location of distal tear on hemodynamics and wave propagation in type B aortic dissection[J]. Applied Mathematics and Mechanics (English Edition), 2022, 43(9): 1449-1468.

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Effects of size and location of distal tear on hemodynamics and wave propagation in type B aortic dissection

Effects of size and location of distal tear on hemodynamics and wave propagation in type B aortic dissection

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