Abstract: Because of the extensive applications of nonlinear ordinary differential equation in physics,mechanics and cybernetics,there have been many papers on the exact solution to differential equation in some major publications both at home and abroad in recent years Based on these papers and in virtue of Leibniz formula,and transformation set technique,this paper puts forth the solution to nonlinear ordinary differential equation set of higher-orders, moveover,its integrability is proven.The results obtained are the generalization of those in the references.