THE STEADY/PULSATILE FLOW AND MACROMOLECULAR TRANSPORT IN T-BIFURCATION BLOOD VESSELS

Applied Mathematics and Mechanics (English Edition) ›› 2003, Vol. 24 ›› Issue (5): 532-544.

THE STEADY/PULSATILE FLOW AND MACROMOLECULAR TRANSPORT IN T-BIFURCATION BLOOD VESSELS

李丁, 温功碧

Department of Mechanics and Engineering Science, State Key Laboratory for Turbulence and Complicated System Research, Peking University, Beijing 100871, P.R.China

收稿日期:2001-12-28 修回日期:2002-12-08 出版日期:2003-05-18 发布日期:2003-05-18
基金资助:
the National Natural Science Foundation of China(10002003)

THE STEADY/PULSATILE FLOW AND MACROMOLECULAR TRANSPORT IN T-BIFURCATION BLOOD VESSELS

LI Ding, WEN Gong-bi

Department of Mechanics and Engineering Science, State Key Laboratory for Turbulence and Complicated System Research, Peking University, Beijing 100871, P.R.China

Received:2001-12-28 Revised:2002-12-08 Online:2003-05-18 Published:2003-05-18
Supported by:
the National Natural Science Foundation of China(10002003)

摘要/Abstract

摘要： A numerical analysis of the steady and pulsatile, macromolecular(such as low density lipopotein(LDL), Albumin)transport in T-bifurcation was proposed. The influence of Reynolds number and mass flow ratio etc. parameters on the velocity field and mass transport were calculated. The computational results predict that the blood flow factors affect the macromolecular distribution and the transport across the wall, it shows that hemodynamic play an important role in the process of atherosclerosis. The LDL and Albumin concentration on the wall varies most greatly in flow bifurcation area where the wall shear stress varies greatly at the branching vessel and the atherosclerosis often appears there.

Abstract: A numerical analysis of the steady and pulsatile, macromolecular(such as low density lipopotein(LDL), Albumin)transport in T-bifurcation was proposed. The influence of Reynolds number and mass flow ratio etc. parameters on the velocity field and mass transport were calculated. The computational results predict that the blood flow factors affect the macromolecular distribution and the transport across the wall, it shows that hemodynamic play an important role in the process of atherosclerosis. The LDL and Albumin concentration on the wall varies most greatly in flow bifurcation area where the wall shear stress varies greatly at the branching vessel and the atherosclerosis often appears there.

中图分类号:

R318.01

李丁;温功碧. THE STEADY/PULSATILE FLOW AND MACROMOLECULAR TRANSPORT IN T-BIFURCATION BLOOD VESSELS[J]. Applied Mathematics and Mechanics (English Edition), 2003, 24(5): 532-544.

LI Ding;WEN Gong-bi. THE STEADY/PULSATILE FLOW AND MACROMOLECULAR TRANSPORT IN T-BIFURCATION BLOOD VESSELS[J]. Applied Mathematics and Mechanics (English Edition), 2003, 24(5): 532-544.

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THE STEADY/PULSATILE FLOW AND MACROMOLECULAR TRANSPORT IN T-BIFURCATION BLOOD VESSELS

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